Simultaneous and Direct Determination of Vancomycin and Cephalexin in Human Plasma by Using HPLC-DAD Coupled with Second-Order Calibration Algorithms

Table 2

Analytical figure of merit.

	SWALTD		PARAFAC
Figure of merit^a	Vancomycin	Cephalexin	Vancomycin	Cephalexin
Sensitivity (SEN), ABS, mL/mg	1.009	1.920	0.8921	1.301
Selectivity (SEL)	0.105	0.235	0.102	0.238
LOD, mg/mL	0.32	0.047	0.12	0. 026

^aABS is the absorption intensity (arbitrary units).