Direct Analysis of Pharmaceutical Drugs Using Nano-DESI MS

Figure 2

Mass spectra from direct tablet analysis using nano-DESI MS; (a) ibuprofen containing tablet, showing ibuprofen specific fragment ions at m/z 119 and 161, (b) paracetamol containing tablet, showing paracetamol specific fragment ions at m/z 110 and 152, (c) sildenafil containing tablet, showing specific sildenafil m/z 475 ion and m/z 513 ion, and (d) tadalafil containing tablet, showing specific tadalafil m/z 412 ion and lactose m/z 365 ion.

(a)

(b)

(c)

(d)