Evaluation of Global Genomic DNA Methylation in Human Whole Blood by Capillary Electrophoresis UV Detection

Table 1

Interassay precision of the quality control samples calf thymus DNA or human leukocyte (HL) of our CE method compared to other published values.

Interassay CV%	Sample	Analytical method	Reference
3.5	Calf thymus	HPLC-ESI-MS/MS	[12]
5.7	HL DNA	HPLC-ESI-MS/MS	[13]
5.58–6.06	HL DNA	HPLC-MS/MS	[14]
4.92	HL DNA	HPLC-MS/MS	[15]
3.8	Calf thymus	HPLC-UV	[16]
15	Calf thymus	HPLC-UV	[17]
<4	Calf thymus	UPLC-UV	[18]
<15	HL DNA	GC-MS	[19]
7	Calf thymus	GC-MS	[20]
6.5^a	Calf thymus	GC-MS	[21]
3.0	Calf thymus	GC-FID	[22]
8.2^a	Calf thymus	GC-ECD	[23]
<5	Calf thymus	CE-LIF	[24]
<5	Calf thymus	CE-UV	[25]
3.2	HL DNA	CE-UV	[26]
3.3	HL DNA	CE-UV	[27]
1.98	HL DNA	CE-UV	Our method

^aData published in mol% are converted to 5-methylcytosine/total cytosine ratio.