Simultaneous Determination of 11 Compounds in Gualou Guizhi Granule and Pharmacokinetics Study by UPLC-MS/MS

Figure 1

Chemical structures of the eleven standard reference compounds and ISs. 1: paeoniflorin; 2: albiflorin; 3: liquiritin; 4: isoliquiritin; 5: liquiritin apioside; 6: isoliquiritin apioside; 8: liquiritigenin; 9: isoliquiritigenin; 10: glycyrrhizic acid; 11: glycyrrhetinic acid; 12: paeoniflorin sulfonate; IS1: ginsenoside Rb1; IS2: swertiamarin; IS3: kaempferol-3-O-rutinoside.