Simultaneous Determination of 11 Compounds in Gualou Guizhi Granule and Pharmacokinetics Study by UPLC-MS/MS

Table 2

Calibration curves and linear ranges of detected compounds (n = 8).

Analyte	Regression equation	r	Linear range (μg/mL)
Paeoniflorin		r = 0.9980	0.040–8.00
Albiflorin		r = 0.9597	0.040–10.00
Liquiritin		r = 0.9930	0.005–1.00
Isoliquiritin		r = 0.9644	0.005–0.50
Liquirtin apioside		r = 0.9970	0.005–0.50
Isoliquiritin apioside		r = 0.9737	0.005–0.50
Liquiritigenin		r = 0.9910	0.001–0.20
Isoliquiritigenin		r = 0.9813	0.001–0.20
Glycyrrhizic acid		r = 0.9813	0.050–1.00
Glycyrrhetinic acid		r = 0.9985	0.010–4.00
Paeoniflorin sulfonate		r = 0.9985	0.050–11.25