Simultaneous Quantitative Determination of Synthetic Cathinone Enantiomers in Urine and Plasma Using GC-NCI-MS

Table 2

List of the 36 cathinone-related compounds and their synonyms, in addition to the retention times of the separated two diastereoisomers for each compound analyzed by GC-MS using SIM mode.

	Name	Synonyms	Time (min)		FWHM		Resolution	Selectivity factor (α)
			tR1	tR2	P1	P2
1	2-Methoxymethcathinone	2-MeOMC	48.98	49.98	0.061	0.062	9.59	1.03
2	3-Fluoroethcathinone	3-FEC	43	43.3	0.066	0.068	2.64	1.01
3	4-Fluoroethcathinone	4-FEC	42.7	43.2	0.084	0.086	3.47	1.01
4	2,3-Methylenedioxymethcathinone	2,3-MDMC	55.1	56.4	0.078	0.075	10.03	1.03
5	2-Methylmethcathinone	2-MMC	45.1	46.2	0.065	0.07	9.61	1.03
6	Nor-mephedrone	—	44.9	47.2	0.078	0.081	17.07	1.06
7	4-Ethylethcathinone	4-EEC	51.6	52.5	0.075	0.076	7.03	1.02
8	3,4-Dimethylethcathinone	3,4-DMEC	52.8	53.6	0.072	0.072	6.56	1.02
9	2-Ethylmethcathinone	2-EMC	47.5	48.6	0.064	0.07	9.69	1.03
10	3-Methoxymethcathinone	3-MeOMC	51.4	51.7	0.059	0.06	2.97	1.01
11	2-Fluoromethcathinone	2-FMC	41.9	43	0.073	0.076	8.71	1.03
12	4-Ethylmethcathinone	4-EMC	50.5	51.7	0.061	0.061	11.61	1.03
13	3-Ethylethcathinone	3-EEC	50.4	51	0.078	0.072	4.72	1.01
14	4-Methylbuphedrone	—	48.96	49.4	0.074	0.078	3.42	1.01
15	2,3-Dimethylmethcathinone	2,3-DMMC	49.7	51.1	0.062	0.069	12.61	1.03
16	3-Ethylmethcathinone	3-EMC	49.8	50	0.078	0.074	1.55	1.00
17	3-Fluoromethcathinone	3-FMC	41.7	41.98	0.07	0.065	2.45	1.01
18	4-Fluoromethcathinone	4-FMC	41.5	41.96	0.092	0.084	3.08	1.01
19	2-Methylethcathinone	2-MEC	46.3	47.6	0.073	0.068	10.88	1.03
20	Buphedrone	—	45.2	45.4	0.079	0.08	1.48	1.01
21	4-Methyl-α-ethylaminobutiophenone	—	49.7	50.3	0.061	0.061	5.80	1.01
22	Pentedrone	—	47.6	47.7	0.057	0.053	1.07	1.00
23	Butylone	—	59.7	60.6	0.091	0.091	5.84	1.02
24	Pentylone	—	62.6	63.2	0.105	0.103	3.40	1.01
25	4-Methylethcathinone	4-MEC	48	49.2	0.058	0.063	11.70	1.03
26	Ethcathinone	—	44.2	44.9	0.067	0.067	6.16	1.02
27	3-Methylmethcathinone	3-MMC	46.3	47	0.078	0.077	5.33	1.02
28	4-Bromomethcathinone	4-BMC	53.96	54.3	0.069	0.068	2.93	1.01
29	3-Bromomethcathinone	3-BMC	42.9	43.6	0.090	0.085	4.72	1.02
30	2,4-Dimethylmethcathinone	2,4-DMMC	48.5	49.96	0.063	0.063	13.67	1.04
31	2,4-Dimethylethcathinone	2,4-DMEC	49.8	51.2	0.065	0.071	12.15	1.03
32	3,4-Methylenedioxy-N-ethylcathinone	Ethylone	58.6	59.9	0.075	0.079	9.96	1.03
33	3-Methylbuphedrone	—	48.4	48.5	0.074	0.074	0.80	1.00
34	N-ethylbuphedrone	NEB	45.9	46.1	0.061	0.061	1.93	1.01
35	2,3-Pentylone isomer	—	59.1	59.9	0.058	0.07	7.37	1.02
36	3-Methylethcathinone	3-MEC	47.4	48.1	0.063	0.061	6.66	1.02