Research Article

Determination of Fluoroquinolones in Pharmaceutical Formulations by Extractive Spectrophotometric Methods Using Ion-Pair Complex Formation with Bromothymol Blue

Table 4

The results of analysis of pharmaceutical preparation and standard of fluoroquinolones by two different analysts and instruments ().

MethodDifferent instrumentsDifferent analysts
X±SDRSD (%)X±SDRSD (%)

Ofloxacin-BTB pure ofloxacin (10 µg·mL−1) Mekopharm (200 mg ofloxacin per tablet)10.210.191.869.930.242.42
1990.570.291960.760.39

Levofloxacin-BTB pure levofloxacin (10 µg·mL−1) Stada (500 mg levofloxacin per tablet)10.160.151.4810.190.212.06
4980.610.125010.850.17

Ciprofloxacin-BTB pure ciprofloxacin (10 µg·mL−1) Hasancip (500 mg ciprofloxacin per tablet)9.850.181.8310.120.252.47
5020.640.134970.920.19