Pharmacokinetics and Bioavailability Study of Tubeimoside I in ICR Mice by UPLC-MS/MS

Table 3

The pharmacokinetic parameters of TBMS-I after oral and intravenous administration ().

Parameters	Unit	iv (5 mg/kg)	po (20 mg/kg)
AUC (0–t)	ng/mL·h	51205.8 ± 13134.0	2023.9 ± 1145.5
AUC (0–∞)	ng/mL·h	59370.3 ± 21468.0	2051.8 ± 1106.5
MRT (0–t)	h	5.1 ± 1.8	4.6 ± 2.4
MRT (0–∞)	h	8.9 ± 7.0	4.9 ± 2.0
t1/2z	h	6.8 ± 5.6	2.3 ± 0.5
CLz/F	L/h/kg	0.1	16.3 ± 17.4
Tmax	H	—	1.8 ± 1.3
Vz/F	L/kg	0.4	53.9 ± 56.9
Cmax	ng/mL	26192.5 ± 8491.9	429.6 ± 164.9