Research Article

Comparative Study of Chemical Stability of Two H1 Antihistaminic Drugs, Terfenadine and Its In Vivo Metabolite Fexofenadine, Using LC-UV Methods

Figure 1

(a) In vivo conversion of terfenadine (TER) to fexofenadine (FEX); (b) isocationic and neutral forms of TER; (c) isocationic, neutral, and isoanionic forms of FEX.