Simultaneous Determination of Five Chromones of Radix Saposhnikoviae Extract in Rat Plasma by UPLC-MS/MS: Application to a Comparative Pharmacokinetic Study in Normal and Febrile Rats

Figure 1

The chemical structures and full-scan product ion spectra of prim-O-glucosylcimifugin (a), cimifugin (b), 4′-O-β-D-glucosyl-5-O-methylvisamminol (c), 5-O-methylvisamminol (d), sec-O-glucosylhamaudol (e), and puerarin (IS) (f) in the positive ionization mode.

(a)

(b)

(c)

(d)

(e)

(f)