Simultaneous Determination of Five Chromones of Radix Saposhnikoviae Extract in Rat Plasma by UPLC-MS/MS: Application to a Comparative Pharmacokinetic Study in Normal and Febrile Rats

Figure 3

Mean plasma concentration-time curves for (a) prim-O-glucosylcimifugin, (b) cimifugin, (c) 4′-O-β-D-glucosyl-5-O-methylvisamminol, (d) 5-O-methylvisamminol, and (e) sec-O-glucosylhamaudol in normal and febrile rats after oral administration of RS extract, repectively ().

(a)

(b)

(c)

(d)

(e)