Simultaneous Determination of Five Chromones of Radix Saposhnikoviae Extract in Rat Plasma by UPLC-MS/MS: Application to a Comparative Pharmacokinetic Study in Normal and Febrile Rats

Table 2

The regression equations and lower limit of quantification of the analytes.

Analytes	RT (min)	Calibration curves	R	Liner range (μg/mL)	LLOQ (μg/mL)
prim-O-glucosylcimifugin	3.04	y = 31.488x + 0.117	0.9902	0.008–3.170	0.008
Cimifugin	3.73	y = 32.072x + 0.110	0.9950	0.033–13.220	0.033
4′-O-β-D-glucosyl-5-O-methylvisamminol	4.01	y = 49.868x + 0.039	0.9913	0.003–1.234	0.003
5-O-methylvisamminol	4.84	y = 161.731x + 0.062	0.9976	0.011–4.434	0.011
sec-O-glucosylhamaudol	5.06	y = 63.046x + 0.770	0.9957	0.001–0.552	0.001