The Application of CA and PCA to the Evaluation of Lipophilicity and Physicochemical Properties of Tetracyclic Diazaphenothiazine Derivatives

Table 2

The values of the R_M0 parameter obtained on the basis of the equation R_M = R_M0 + (b)C and the value of log P_TLC for the 1–11 derivatives.

No	RM0	−b	r	SD	log PTLC
1	2.3379	0.0278	0.9957	0.0470	3.53
2	3.2293	0.0391	0.9924	0.0882	4.83
3	3.0699	0.0361	0.9900	0.0935	4.61
4	3.1016	0.0377	0.9907	0.0943	4.65
5	2.8262	0.0343	0.9946	0.0648	4.25
6	3.4373	0.0410	0.9900	0.1062	5.14
7	3.8299	0.0450	0.9934	0.0943	5.72
8	3.8738	0.0463	0.9913	0.1122	5.78
9	2.7871	0.0333	0.9906	0.0850	4.19
10	2.8087	0.0325	0.9941	0.0649	4.22
11	1.9173	0.0241	0.9961	0.0386	2.92