Bioguided Isolation and Structure Identification of Acetylcholinesterase Enzyme Inhibitors from Drynariae Rhizome

<table class="table-group" id="tab3"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td class="align_left">Compounds</td><td class="align_center">IC<sub>50</sub> (<i>μ</i>M ± SD)</td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td class="align_left">Galantamine</td><td class="align_center">1.26 ± 0.15</td></tr><tr><td class="align_left">Naringenin</td><td class="align_center">3.81 ± 0.21</td></tr><tr><td class="align_left">Eriodictyol</td><td class="align_center">7.19 ± 0.62</td></tr><tr><td class="align_left">Kaempferol</td><td class="align_center">11.09 ± 1.02</td></tr><tr><td class="align_left">Luteolin</td><td class="align_center">17.26 ± 0.23</td></tr><tr><td class="align_left">Astragalin</td><td class="align_center">18.24 ± 2.33</td></tr><tr><td class="align_left">Luteolin-7-O-<i>β</i>-D-glucoside</td><td class="align_center">17.13 ± 1.02</td></tr><tr><td class="align_left">Naringin</td><td class="align_center">26.4 ± 1.17</td></tr><tr><td class="align_left">Neoeriocitrin</td><td class="align_center">22.49 ± 1.25</td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Inhibitory activity (IC<sub>50</sub>) of the tested compounds investigated against AChE (<i>n</i> = 6).</div>

Journal of Analytical Methods in Chemistry

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Table 3

Table 3: Bioguided Isolation and Structure Identification of Acetylcholinesterase Enzyme Inhibitors from Drynariae Rhizome 