Research Article

Pharmacokinetic Comparisons of Eight Active Components from Raw Farfarae Flos and Honey-Processed Farfarae Flos after Oral Administration in Rats by UHPLC-MS/MS Approaches

Table 2

The regression equations, linear range, and LLOQs of the 8 analytes.

AnalytesRange (ng/mL)Calibration curvesCorrelation coefficient (r2)LLOQ (ng/mL)

Ferulic acid2.05–1000.00y = 0.027x−0.8570.9932.05
Caffeic acid2.78–8840.00y = 0.035x−14.3940.9992.78
Chlorogenic acid4.35–118500.00y = 0.002x−1.5660.9994.35
Neochlorogenic acid2.67–39000.00y = 0.013x−2.9140.9902.67
Cryptochlorogenic acid2.38–168000.00y = 0.032x−32.2660.9902.38
Isochlorogenic acid B1.30–211000.00y = 0.031x−2.3700.9911.30
Isochlorogenic acid C4.87–230000.00y = 0.057x−9.0970.9904.87
Rutin1.45–8150.00y = 0.020x + 1.0450.9941.45