Pharmacokinetic Comparisons of Eight Active Components from Raw Farfarae Flos and Honey-Processed Farfarae Flos after Oral Administration in Rats by UHPLC-MS/MS Approaches

Table 3

Intraday and interday accuracy and precision of 8 analytes.

Analytes	Spiked concentration (ng/ml)	Intraday (n = 6)		Interday (n = 6)
		Accuracy (RE, %)	Precision (RSD, %)	Accuracy (RE, %)	Precision (RSD, %)
Ferulic acid	100.00	4.09	3.48	4.73	4.89
	200.00	1.42	1.12	3.79	3.92
	500.00	2.14	2.18	4.81	3.55
Caffeic acid	380.00	1.43	3.08	−5.11	3.57
	3800.00	4.34	3.63	4.31	3.27
	6000.00	−1.19	1.22	2.45	4.55
Chlorogenic acid	3500.00	−3.24	2.79	−4.54	3.75
	40400.00	−1.20	1.26	−3.56	3.78
	110000.00	−3.72	2.41	4.70	4.03
Neochlorogenic acid	1000.00	−3.15	3.61	4.37	4.51
	15000.00	1.07	2.83	2.00	2.64
	25000.00	1.06	1.85	−3.78	4.30
Cryptochlorogenic acid	2000.00	2.63	3.65	4.84	3.82
	50000.00	1.28	1.95	2.65	2.18
	100000.00	2.47	2.93	3.99	2.44
Isochlorogenic acid B	2000.00	1.56	1.84	3.90	3.51
	80000.00	−2.30	2.47	−2.24	4.79
	160000.00	1.19	2.33	2.39	3.47
Isochlorogenic acid C	1500.00	1.53	3.92	4.09	4.65
	7500.00	−2.45	2.88	4.23	3.02
	140000.00	−1.42	2.72	4.46	4.94
Rutin	600.00	1.78	3.98	3.85	3.00
	4000.00	2.41	2.64	4.38	2.10
	8000.00	1.04	2.35	2.87	4.81
Chloramphenicol (IS)	100	1.11	1.26	3.06	3.48