Comparative Pharmacokinetic Profiles of Puerarin in Rat Plasma by UHPLC-MS/MS after Oral Administration of Pueraria lobata Extract and Pure Puerarin

Table 4

Stability of PUR in rat plasma by the UHPLC-MS/MS method (n = 3).

Marker compounds	Concentration (ng/mL)	Stability (RE, %)
		Freeze-thaw (3 cycles)	23°C–28°C/24 h	−20°C/30 day	Postextraction
PUR	8.0	9.3	11.5	11.4	−7.7
	80.0	5.6	6.5	6.2	−6.3
	720.0	−5.1	8.7	−4.7	5.9