A Validated Volumetric Absorptive Microsampling-Liquid Chromatography Tandem Mass Spectrometry Method to Quantify Doxycycline Levels in Urine: An Application to Monitor the Malaria Chemoprophylaxis Compliance

<div>Overlay of typical multiple reactions monitoring mode chromatograms for tetracycline (a) and doxycycline (b) obtained from blank human urine (red line) and urine spiked with the LLOQ concentration (blue line) after extraction of the microsampling device.</div>

Journal of Analytical Methods in Chemistry

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Figure 1: A Validated Volumetric Absorptive Microsampling-Liquid Chromatography Tandem Mass Spectrometry Method to Quantify Doxycycline Levels in Urine: An Application to Monitor the Malaria Chemoprophylaxis Compliance 

Figure 1 | A Validated Volumetric Absorptive Microsampling-Liquid Chromatography Tandem Mass Spectrometry Method to Quantify Doxycycline Levels in Urine: An Application to Monitor the Malaria Chemoprophylaxis Compliance 