A Validated Volumetric Absorptive Microsampling-Liquid Chromatography Tandem Mass Spectrometry Method to Quantify Doxycycline Levels in Urine: An Application to Monitor the Malaria Chemoprophylaxis Compliance

Table 2

Relative standard deviation and recovery from back-calculated concentrations from calibration curves after microsampling and direct dilution (n = 6).

Theoretical concentration (µg/mL)	R.S.D (%)		Recovery (%)
	Microsampling	Direct dilution	Microsampling	Direct dilution
0.25	10.2	8.1	103.7	100.6
0.40	7.5	6.8	98.3	99.8
1.00	4.1	8.4	97.8	99.6
5.00	11.0	10.2	100.0	98.5
12.5	6.0	4.2	98.3	102.5
25.0	5.1	3.8	105.0	99.4
37.5	4.8	2.5	95.9	99.2
50.0	3.0	0.6	101.0	100.5