Research Article

A Validated Volumetric Absorptive Microsampling-Liquid Chromatography Tandem Mass Spectrometry Method to Quantify Doxycycline Levels in Urine: An Application to Monitor the Malaria Chemoprophylaxis Compliance

Table 3

Precision and accuracy of the microsampling and direct dilution methods (n = 12).

Theoretical concentration (µg/mL)Precision (%)Accuracy (%)

MicrosamplingDirect dilutionMicrosamplingDirect dilution

0.259.613.3106.295.4
0.307.99.4102.097.3
20.04.77.5104.8104.8
35.06.68.2104.498.9