Pharmacokinetic Comparisons of Different Combinations of Yigan Jiangzhi Formula in Rats: Simultaneous Determination of Fourteen Components by UPLC-MS/MS

Table 3

The regression equation, linear ranges, and LLOQs of the fourteen analytes in rat plasma.

No.	Analyte	Regression equation (W = 1/x^2)	r	Linear range (ng/mL)	LLOQ (ng/mL)
1	Daidzein	y = 1.0767x + 2.3433	0.9933	0.2–100	0.2
2	Fermononetin	y = 0.1497x + 0.0763	0.9981	0.5–250	0.5
3	Apigenin	y = 0.5257x + 0.1422	0.9975	0.2–100	0.2
4	Luteolin	y = 0.2124x + 0.0092	0.9992	1.0–500	1.0
5	Berberine	y = 1.0672x + 0.7246	0.9979	0.2–100	0.2
6	Jatrorrhizin	y = 1.9106x + 0.3999	0.9985	0.2–100	0.2
7	Palmatine	y = 2.5077x + 0.4315	0.9993	0.2–100	0.2
8	Puerarin	y = 0.1864x + 2.7353	0.9937	2.0–1000	2.0
9	Ononin	y = 1.7778x + 0.1393	0.9980	0.5–250	0.5
10	Calycosin-7-O-β-D-Glc	y = 0.9216x + 0.1215	0.9989	0.2–100	0.2
11	Tanshinol	y = 0.0158x − 0.0041	0.9979	10.0–5000	10.0
12	Rosmarinic acid	y = 0.9884x + 0.0390	0.9943	0.5–250	0.5
13	Alkanoic acid	y = 0.1800x + 0.0130	0.9989	2.0–1000	2.0
14	Salvianolic acid B	y = 0.4326x + 0.0395	0.9987	1.0–500	1.0