Simultaneous Quantification of Four Ginsenosides in Rat Plasma and Its Application to a Comparative Pharmacokinetic Study in Normal and Depression Rats Using UHPLC-MS/MS

Figure 3

Representative multireaction monitoring mode chromatogram of G-Rh₁ (a), G-Rb₁ (b), G-Rc (c), G-Rd (d), and IS (e) in blank plasma (A), blank plasma spiked with four analytes and IS (B), and plasma sample 1 h after oral administration at a dose of 80 mg/kg (C).

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(b)

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(e)