Journal of Analytical Methods in Chemistry

Research Article

Quantitation of Apremilast in Beagle Dogs Plasma by UPLC-MS-MS and Its Application to Pharmacokinetic Studies

Table 2

Extraction recoveries of apremilast and clopidogrel in beagle dog plasma.
CompoundConcentration (ng/mL)Recoveries (%, n = 6)RSD (%)
NominalDetermined/Before extractionDetermined/After extraction
Apremilast5.004.815.5187.45.9
50.0046.0549.0893.85.3
1000.00842.08864.4897.43.3