Binary Eluent Based Vortex-Assisted Matrix Solid-Phase Dispersion for the Extraction and Determination of Multicomponent from Musk by Gas Chromatography-Mass Spectrometry
Table 1
Optimization of the results of the orthogonal experimental design.
No.
Grinding time (A) (min)
Eluent ratio (B) (methanol: ethyl acetate)
Elution volume (C) (mL)
Elution time (D) (min)
Total content (mg·g−1)
1
1
1
1
1
0.36 ± 0.02
2
1
2
2
2
0.36 ± 0.01
3
1
3
3
3
0.33 ± 0.01
4
2
1
2
3
0.39 ± 0.01
5
2
2
3
1
0.38 ± 0.01
6
2
3
1
2
0.34 ± 0.01
7
3
1
3
2
0.37 ± 0.01
8
3
2
1
3
0.37 ± 0.01
9
3
3
2
1
0.33 ± 0.01
K1
0.35
0.37
0.36
0.35
K2
0.37
0.37
0.36
0.36
K3
0.36
0.33
0.36
0.36
R
0.02
0.04
0.01
0.01
Order
B > A > D > C
Optimal level
A2
B2
C3
D3
Optimal combination
A2B2C3D3
Ki: the average of each level in each factor. R: the difference between the maximum and minimum levels of each factor.
