Tissue Distribution of Total Flavonoids Extracts of Drynariae Rhizoma in Young and Old Rats by UPLC–MS/MS Determination

Table 10

Recovery and matrix effect study of neoeriocitrin in rat tissues (n = 6).

Tissues	Spiked (ng/mL)	Recovery		Matrix effects
		Mean (%) ± SD	RSD (%)	Mean (%) ± SD	RSD (%)
Heart	8.10	94.72 ± 14.10	14.89	95.70 ± 13.74	14.36
	121.50	91.22 ± 13.65	14.96	95.21 ± 13.09	13.75
	243.00	105.88 ± 11.56	10.92	109.53 ± 11.31	10.33
Liver	12.20	86.98 ± 9.39	10.80	84.95 ± 9.27	10.91
	610.00	97.31 ± 2.54	2.61	97.17 ± 2.44	2.51
	3,660.00	90.68 ± 7.51	8.28	93.69 ± 6.13	6.54
Spleen	8.10	115.23 ± 7.17	6.22	115.8 ± 6.58	5.68
	810.00	99.6 ± 1.74	1.75	99.59 ± 1.76	1.77
	4,050.00	91.21 ± 10.74	11.78	96.67 ± 11.20	11.59
Lung	12.20	103.66 ± 10.52	10.15	101.25 ± 9.04	8.93
	1,220.00	87.54 ± 10.41	11.89	88.18 ± 9.83	11.15
	4,880.00	95.55 ± 2.68	2.80	96.10 ± 2.62	2.73
Kidney	8.10	114.05 ± 3.81	3.34	115.65 ± 2.59	2.24
	121.50	100.88 ± 14.50	14.37	98.47 ± 14.56	14.79
	243.00	98.5 ± 14.22	14.44	102.34 ± 13.24	12.94
Brain	8.10	111.41 ± 14.50	13.01	112.94 ± 13.84	12.25
	40.50	90.48 ± 13.11	14.49	89.76 ± 13.16	14.66
	81.00	107.02 ± 8.46	7.91	108.47 ± 8.82	8.13
Stomach	8.10	112 ± 12.00	10.71	116.4 ± 8.33	7.16
	810.00	109.15 ± 6.82	6.25	111.59 ± 4.46	4.00
	4,050.00	105.59 ± 7.97	7.55	104.97 ± 8.96	8.54
Uterus	8.10	108.3 ± 14.27	13.18	113.04 ± 14.59	12.91
	121.50	101.6 ± 10.34	10.18	96.07 ± 13.08	13.62
	243.00	97.02 ± 14.20	14.64	96.53 ± 14.07	14.58
Ovary	8.10	98.12 ± 14.25	14.52	98.86 ± 14.13	14.29
	121.50	91.95 ± 9.48	10.31	91.85 ± 9.65	10.51
	243.00	92.92 ± 12.43	13.38	98.22 ± 12.04	12.26
Intestine	8.10	107.31 ± 10.98	10.23	111.09 ± 7.96	7.17
	810.00	97.25 ± 7.34	7.55	94.24 ± 3.12	3.31
	4,050.00	106.03 ± 10.66	10.05	102.82 ± 10.25	9.97