Tissue Distribution of Total Flavonoids Extracts of Drynariae Rhizoma in Young and Old Rats by UPLC–MS/MS Determination

Table 13

Recovery and matrix effect study of naringin in rat tissues (n = 6).

Tissues	Spiked (ng/mL)	Recovery		Matrix effects
		Mean (%) ± SD	RSD (%)	Mean (%) ± SD	RSD (%)
Heart	8.10	110.00 ± 14.19	12.90	117.51 ± 14.62	12.44
	405.00	93.51 ± 11.82	12.64	93.89 ± 11.91	12.69
	810.00	101.07 ± 8.60	8.51	105.49 ± 8.39	7.95
Liver	12.20	97.87 ± 10.65	10.88	99.51 ± 9.41	9.46
	1,220.00	89.61 ± 11.61	12.96	90.30 ± 11.09	12.28
	4,880.00	99.40 ± 13.63	13.71	103.70 ± 14.18	13.67
Spleen	8.10	109.60 ± 14.70	13.41	112.52 ± 14.42	12.82
	810.00	103.36 ± 8.21	7.94	103.27 ± 8.33	8.07
	4,050.00	101.09 ± 14.04	13.89	100.10 ± 14.86	14.85
Lung	8.10	115.98 ± 9.88	8.52	114.91 ± 11.15	9.70
	810.00	103.72 ± 13.87	13.37	104.46 ± 13.99	13.39
	4,050.00	100.14 ± 13.93	13.91	102.61 ± 12.94	12.61
Kidney	8.10	112.86 ± 13.55	12.01	106.12 ± 6.39	6.02
	810.00	108.24 ± 11.67	10.78	106.49 ± 12.47	11.71
	4,050.00	96.03 ± 14.21	14.80	100.79 ± 13.41	13.30
Brain	8.10	102.10 ± 14.19	13.90	102.74 ± 13.52	13.16
	405.00	102.58 ± 14.19	13.83	99.34 ± 11.32	11.40
	810.00	106.80 ± 14.57	13.64	107.01 ± 14.37	13.43
Stomach	8.10	107.26 ± 14.80	13.80	114.20 ± 12.91	11.30
	810.00	97.56 ± 12.51	12.82	93.00 ± 7.55	8.12
	8,100.00	96.18 ± 7.88	8.19	96.52 ± 7.87	8.15
Uterus	8.10	114.62 ± 8.67	7.56	112.15 ± 12.13	10.82
	1,215.00	101.9 ± 14.88	14.60	103.53 ± 14.50	14.01
	2,430.00	98.79 ± 13.24	13.40	93.95 ± 10.73	11.42
Ovary	8.10	107.31 ± 13.35	12.44	110.67 ± 12.10	10.93
	810.00	105.44 ± 7.65	7.26	107.56 ± 6.27	5.83
	4,050.00	101.35 ± 12.01	11.85	97.01 ± 11.43	11.78
Intestine	8.10	104.91 ± 14.63	13.95	110.86 ± 14.79	13.34
	810.00	102.29 ± 13.48	13.18	104.20 ± 13.93	13.37
	8,100.00	106.06 ± 13.22	12.46	104.55 ± 14.54	13.91