Tissue Distribution of Total Flavonoids Extracts of Drynariae Rhizoma in Young and Old Rats by UPLC–MS/MS Determination

Table 14

Recovery and matrix effect study of eriodictyol in rat tissues (n = 6).

Tissues	Spiked (ng/mL)	Recovery		Matrix effects
		Mean (%) ± SD	RSD (%)	Mean (%) ± SD	RSD (%)
Liver	8.10	106.86 ± 14.59	13.65	109.83 ± 14.69	13.38
	40.50	91.41 ± 7.79	8.52	94.49 ± 11.13	11.78
	81.00	105.18 ± 14.43	13.72	105.09 ± 14.48	13.78
Spleen	5.05	95.80 ± 11.70	12.21	96.04 ± 11.87	12.36
	10.10	113.03 ± 10.54	9.32	115.70 ± 9.70	8.38
	25.25	92.38 ± 10.17	11.01	87.52 ± 10.86	12.41
Lung	8.10	109.31 ± 8.93	8.17	108.1 ± 11.23	10.39
	40.50	104.59 ± 14.51	13.87	104.43 ± 14.71	14.09
	81.00	96.59 ± 9.92	10.27	101.09 ± 14.34	14.19
Stomach	8.10	110.96 ± 14.26	12.85	117.43 ± 12.96	11.04
	81.00	99.02 ± 7.86	7.94	102.27 ± 9.24	9.03
	162.00	100.60 ± 14.07	13.99	99.81 ± 14.66	14.69
Uterus	5.05	102.46 ± 14.89	14.53	108.36 ± 10.90	10.06
	10.10	103.13 ± 13.69	13.27	99.58 ± 11.98	12.03
	25.25	89.11 ± 12.68	14.23	91.09 ± 12.37	13.58
Ovary	8.10	106.91 ± 11.88	11.11	109.58 ± 14.54	13.27
	40.50	96.92 ± 13.41	13.84	95.40 ± 11.35	11.90
	81.00	110.09 ± 8.83	8.02	110.08 ± 8.87	8.06
Intestine	8.10	112.94 ± 12.47	11.04	106.15 ± 14.11	13.29
	81.00	96.66 ± 12.21	12.63	101.40 ± 12.07	11.90
	162.00	106.34 ± 12.84	12.07	110.76 ± 12.31	11.11