Tissue Distribution of Total Flavonoids Extracts of Drynariae Rhizoma in Young and Old Rats by UPLC–MS/MS Determination

Table 15

Recovery and matrix effect study of naringenin in rat tissues (n = 6).

Tissues	Spiked (ng/mL)	Recovery		Matrix effects
		Mean (%) ± SD	RSD (%)	Mean (%) ± SD	RSD (%)
Heart	8.10	99.16 ± 14.17	14.29	102.00 ± 14.02	13.75
	81.00	103.12 ± 11.80	11.44	105.54 ± 8.27	7.84
	162.00	99.88 ± 14.63	14.65	101.40 ± 14.36	14.16
Liver	8.10	108.35 ± 14.84	13.70	109.38 ± 14.68	13.42
	405.00	108.53 ± 11.75	10.83	107.65 ± 13.09	12.16
	810.00	97.99 ± 10.82	11.04	97.58 ± 11.39	11.67
Spleen	8.10	110.94 ± 10.73	9.67	116.25 ± 12.71	10.93
	81.00	104.08 ± 8.55	8.21	108.27 ± 5.36	4.95
	162.00	92.22 ± 11.76	12.75	95.49 ± 12.40	12.99
Lung	8.10	112.86 ± 13.55	12.01	103.65 ± 10.11	9.75
	81.00	99.40 ± 12.26	12.33	100.99 ± 10.33	10.23
	162.00	98.08 ± 14.04	14.31	91.96 ± 11.15	12.12
Kidney	8.10	104.57 ± 14.45	13.82	106.32 ± 14.62	13.75
	81.00	101.85 ± 12.04	11.82	104.27 ± 9.04	8.67
	162.00	105.15 ± 11.94	11.36	103.82 ± 14.64	14.10
Brain	5.05	95.80 ± 12.56	13.11	91.80 ± 13.49	14.69
	10.10	108.75 ± 14.63	13.45	110.61 ± 14.02	12.68
	25.25	101.59 ± 12.78	12.58	106.93 ± 13.84	12.94
Stomach	8.10	106.79 ± 11.36	10.64	114.59 ± 13.26	11.57
	405.00	103.98 ± 14.21	13.67	105.46 ± 13.01	12.34
	810.00	105.33 ± 12.86	12.21	98.97 ± 9.74	9.84
Uterus	8.10	109.68 ± 11.56	10.54	105.90 ± 14.62	13.81
	81.00	96.79 ± 14.42	14.90	100.89 ± 13.01	12.90
	162.00	101.76 ± 14.35	14.10	103.84 ± 14.15	13.63
Ovary	8.10	104.12 ± 14.06	13.50	104.27 ± 13.92	13.35
	81.00	102.55 ± 13.60	13.26	102.73 ± 13.50	13.14
	162.00	97.63 ± 12.88	13.19	104.93 ± 12.09	11.52
Intestine	8.10	94.69 ± 11.62	12.27	95.33 ± 11.33	11.89
	405.00	102.26 ± 13.81	13.50	102.21 ± 13.87	13.57
	810.00	95.59 ± 11.24	11.76	95.96 ± 11.07	11.54