Tissue Distribution of Total Flavonoids Extracts of Drynariae Rhizoma in Young and Old Rats by UPLC–MS/MS Determination

Table 3

Interday and intraday precision and accuracy data for assays of neoeriocitrin in different tissues (n = 6).

Tissues	Spiked (ng/mL)	Interday			Intraday
		Mean ± SD	Precision (RSD, %)	Relative error (RE, %)	Mean ± SD	Precision (RSD, %)	Relative error (RE, %)
Heart	8.10	7.54 ± 1.12	14.85	−6.91	7.96 ± 1.17	14.70	−1.73
	121.50	112.95 ± 15.71	13.91	−7.04	113.71 ± 16.05	14.11	−6.41
	243.00	261.48 ± 27.13	10.38	7.60	262.09 ± 29.96	11.43	7.86
Liver	12.20	10.49 ± 1.06	10.10	−14.02	10.47 ± 1.27	12.13	−14.18
	610.00	594.67 ± 14.10	2.37	−2.51	590.92 ± 16.50	2.79	−3.13
	3,660.00	3,358.79 ± 264.49	7.87	−8.23	3,397.03 ± 245.48	7.23	−7.18
Spleen	8.10	9.28 ± 0.54	5.82	14.57	9.17 ± 0.57	6.22	13.21
	810.00	803.86 ± 14.51	1.81	−0.76	811.04 ± 12.00	1.48	0.13
	4,050.00	3,809.56 ± 481.25	12.63	−5.94	3,797.20 ± 425.73	11.21	6.24
Lung	12.20	12.59 ± 1.15	9.13	3.20	12.35 ± 1.27	10.28	1.23
	1,220.00	1,056.82 ± 116.83	11.05	−13.38	1,094.38 ± 129.81	11.86	−10.30
	4,880.00	4,674.43 ± 120.35	2.57	−4.21	4,678.96 ± 145.06	3.10	−4.12
Kidney	8.10	9.27 ± 0.29	3.13	14.44	9.04 ± 0.23	2.54	11.60
	121.50	122.73 ± 17.94	14.62	1.01	118.66 ± 16.84	14.19	−2.34
	243.00	240.32 ± 35.32	14.70	−1.10	249.55 ± 37.09	14.86	2.70
Brain	8.10	8.80 ± 1.31	14.89	8.64	9.21 ± 0.89	9.66	13.70
	40.50	35.93 ± 5.23	14.56	−11.28	37.35 ± 5.10	13.65	−7.78
	81.00	87.50 ± 6.45	7.37	8.02	86.92 ± 7.89	9.08	7.31
Stomach	8.10	9.15 ± 0.89	9.73	12.96	8.38 ± 0.77	9.19	3.46
	810.00	888.08 ± 50.38	5.67	9.64	902.84 ± 41.59	4.61	11.46
	4,050.00	4,190.72 ± 365.94	8.73	3.47	4,373.61 ± 275.62	6.30	7.99
Uterus	8.10	8.86 ± 1.27	14.33	9.38	9.11 ± 1.36	14.93	12.47
	121.50	119.15 ± 15.40	12.92	−1.93	121.49 ± 13.61	11.20	−0.01
	243.00	233.53 ± 32.20	13.79	−3.90	237.59 ± 25.69	10.81	−2.23
Ovary	8.10	7.95 ± 1.03	12.96	−1.85	8.01 ± 1.02	12.73	−1.11
	121.50	109.23 ± 11.97	10.96	−10.10	115.29 ± 9.59	8.32	−5.11
	243.00	231.95 ± 30.92	13.33	−4.55	232.67 ± 30.02	12.90	−4.25
Intestine	8.10	8.76 ± 0.81	9.25	8.15	8.96 ± 0.74	8.26	10.62
	810.00	783.47 ± 54.18	6.92	−3.28	763.63 ± 29.14	3.82	-5.72
	4,050.00	4,236.54 ± 411.35	9.71	4.61	4,218.46 ± 458.40	10.87	4.16