Tissue Distribution of Total Flavonoids Extracts of Drynariae Rhizoma in Young and Old Rats by UPLC–MS/MS Determination

Table 6

Interday and intraday precision and accuracy data for assays of naringin in different tissues (n = 6).

Tissues	Spiked (ng/mL)	Interday			Intraday
		Mean ± SD	Precision (RSD, %)	Relative error (RE, %)	Mean ± SD	Precision (RSD, %)	Relative error (RE, %)
Heart	8.10	9.24 ± 1.38	14.94	14.07	9.16 ± 1.26	13.76	13.09
	405.00	380.94 ± 43.17	11.33	−5.94	377.25 ± 55.15	14.62	−6.85
	810.00	836.12 ± 75.60	9.04	3.22	837.23 ± 64.62	7.72	3.36
Liver	12.20	11.91 ± 1.16	9.74	−2.38	12.22 ± 1.31	10.72	0.16
	1,220.00	1,083.38 ± 128.98	11.91	−11.20	1,118.43 ± 150.05	13.42	−8.33
	4,880.00	4,989.75 ± 685.15	13.73	2.25	4,904.97 ± 645.18	13.15	0.51
Spleen	8.10	9.10 ± 1.26	13.85	12.35	8.83 ± 1.26	14.27	9.01
	810.00	825.26 ± 66.35	8.04	1.88	854.30 ± 62.59	7.33	5.47
	4,050.00	4,004.43 ± 587.31	14.67	−1.12	4,178.48 ± 568.58	13.61	3.17
Lung	8.10	9.21 ± 0.84	9.12	13.70	9.15 ± 0.83	9.07	12.96
	810.00	845.41 ± 101.35	11.99	4.37	839.70 ± 119.76	14.26	3.67
	4,050.00	4,011.38 ± 587.19	14.64	−0.95	4,247.34 ± 556.90	13.11	4.87
Kidney	8.10	8.98 ± 1.06	11.80	10.86	8.69 ± 0.54	6.21	7.28
	810.00	863.67 ± 90.41	10.47	6.63	878.63 ± 109.04	12.41	8.47
	4,050.00	3,956.27 ± 574.77	14.53	−2.31	4,029.43 ± 591.13	14.67	−0.51
Brain	8.10	8.13 ± 1.08	13.28	0.37	8.53 ± 1.14	13.36	5.31
	405.00	415.00 ± 51.43	12.39	2.47	399.72 ± 52.49	13.13	−1.30
	810.00	849.97 ± 118.72	13.97	4.93	889.89 ± 130.79	14.70	9.86
Stomach	8.10	8.92 ± 1.22	13.68	10.12	9.03 ± 1.07	11.85	11.48
	810.00	783.57 ± 92.13	11.76	−3.26	754.08 ± 70.59	9.36	−6.90
	8,100.00	7,802.03 ± 571.75	7.33	−3.68	7,806.89 ± 735.92	9.43	−3.62
Uterus	8.10	9.02 ± 0.89	9.87	11.36	9.22 ± 0.73	7.92	13.83
	1,215.00	1,257.33 ± 168.44	13.40	3.48	1,233.89 ± 179.47	14.55	1.55
	2,430.00	2,361.88 ± 303.00	12.83	−2.80	2,311.52 ± 291.80	12.62	−4.88
Ovary	8.10	8.63 ± 1.19	13.79	6.54	9.12 ± 1.06	11.62	12.59
	810.00	857.76 ± 56.18	6.55	5.90	869.99 ± 58.59	6.73	7.41
	4,050.00	4,025.32 ± 476.37	11.83	−0.61	4,004.08 ± 498.00	12.44	−1.13
Intestine	8.10	8.74 ± 1.28	14.65	7.90	8.73 ± 1.21	13.86	7.78
	810.00	848.01 ± 108.63	12.81	4.69	818.73 ± 113.46	13.86	1.08
	8,100.00	8,290.57 ± 1,207.41	14.56	2.35	8,888.41 ± 968.47	10.90	9.73