Research Article

Tissue Distribution of Total Flavonoids Extracts of Drynariae Rhizoma in Young and Old Rats by UPLC–MS/MS Determination

Table 7

Interday and intraday precision and accuracy data for assays of eriodictyol in different tissues (n = 6).

TissuesSpiked (ng/mL)InterdayIntraday
Mean ± SDPrecision (RSD, %)Relative error (RE, %)Mean ± SDPrecision (RSD, %)Relative error (RE, %)

Liver8.108.90 ± 1.2814.389.888.58 ± 1.2514.575.93
40.5038.20 ± 4.0410.58−5.6836.81 ± 3.609.78−9.11
81.0084.30 ± 10.6812.674.0786.45 ± 11.1112.856.73

Spleen5.054.90 ± 0.5511.22−2.974.75 ± 0.6513.68−5.94
10.1011.50 ± 0.988.5213.8611.61 ± 1.129.6514.95
25.2522.66 ± 2.8112.40−10.2622.78 ± 2.6211.50−9.78

Lung8.108.59 ± 0.9010.486.059.11 ± 0.495.3812.47
40.5041.34 ± 5.8214.082.0743.80 ± 5.6712.958.15
81.0081.34 ± 10.4712.870.4278.13 ± 9.2811.88−3.54

Stomach8.109.14 ± 1.3114.3312.849.21 ± 1.1812.8113.70
81.0081.91 ± 7.078.631.1280.93 ± 7.108.77−0.09
162.00159.83 ± 23.1414.48−1.34166.06 ± 24.7214.892.51

Uterus5.055.24 ± 0.7414.123.765.43 ± 0.6311.607.52
10.1010.16 ± 1.3813.580.5910.34 ± 1.3913.442.38
25.2522.68 ± 2.9012.79−10.1822.85 ± 3.5913.09−9.50

Ovary8.108.91 ± 1.0611.9010.008.55 ± 1.0812.635.56
40.5038.38 ± 5.3013.81−5.2339.78 ± 4.7711.99−1.78
81.0087.31 ± 7.869.007.7991.95 ± 4.084.4413.52

Intestine8.108.83 ± 1.1813.369.018.92 ± 1.0111.3210.12
81.0080.17 ± 9.9812.45−1.0280.27 ± 10.2212.73−0.90
162.00175.52 ± 20.2411.538.35176.33 ± 21.6112.268.85