Research Article
Tissue Distribution of Total Flavonoids Extracts of Drynariae Rhizoma in Young and Old Rats by UPLC–MS/MS Determination
Table 7
Interday and intraday precision and accuracy data for assays of eriodictyol in different tissues (n = 6).
| Tissues | Spiked (ng/mL) | Interday | Intraday | Mean ± SD | Precision (RSD, %) | Relative error (RE, %) | Mean ± SD | Precision (RSD, %) | Relative error (RE, %) |
| Liver | 8.10 | 8.90 ± 1.28 | 14.38 | 9.88 | 8.58 ± 1.25 | 14.57 | 5.93 | 40.50 | 38.20 ± 4.04 | 10.58 | −5.68 | 36.81 ± 3.60 | 9.78 | −9.11 | 81.00 | 84.30 ± 10.68 | 12.67 | 4.07 | 86.45 ± 11.11 | 12.85 | 6.73 |
| Spleen | 5.05 | 4.90 ± 0.55 | 11.22 | −2.97 | 4.75 ± 0.65 | 13.68 | −5.94 | 10.10 | 11.50 ± 0.98 | 8.52 | 13.86 | 11.61 ± 1.12 | 9.65 | 14.95 | 25.25 | 22.66 ± 2.81 | 12.40 | −10.26 | 22.78 ± 2.62 | 11.50 | −9.78 |
| Lung | 8.10 | 8.59 ± 0.90 | 10.48 | 6.05 | 9.11 ± 0.49 | 5.38 | 12.47 | 40.50 | 41.34 ± 5.82 | 14.08 | 2.07 | 43.80 ± 5.67 | 12.95 | 8.15 | 81.00 | 81.34 ± 10.47 | 12.87 | 0.42 | 78.13 ± 9.28 | 11.88 | −3.54 |
| Stomach | 8.10 | 9.14 ± 1.31 | 14.33 | 12.84 | 9.21 ± 1.18 | 12.81 | 13.70 | 81.00 | 81.91 ± 7.07 | 8.63 | 1.12 | 80.93 ± 7.10 | 8.77 | −0.09 | 162.00 | 159.83 ± 23.14 | 14.48 | −1.34 | 166.06 ± 24.72 | 14.89 | 2.51 |
| Uterus | 5.05 | 5.24 ± 0.74 | 14.12 | 3.76 | 5.43 ± 0.63 | 11.60 | 7.52 | 10.10 | 10.16 ± 1.38 | 13.58 | 0.59 | 10.34 ± 1.39 | 13.44 | 2.38 | 25.25 | 22.68 ± 2.90 | 12.79 | −10.18 | 22.85 ± 3.59 | 13.09 | −9.50 |
| Ovary | 8.10 | 8.91 ± 1.06 | 11.90 | 10.00 | 8.55 ± 1.08 | 12.63 | 5.56 | 40.50 | 38.38 ± 5.30 | 13.81 | −5.23 | 39.78 ± 4.77 | 11.99 | −1.78 | 81.00 | 87.31 ± 7.86 | 9.00 | 7.79 | 91.95 ± 4.08 | 4.44 | 13.52 |
| Intestine | 8.10 | 8.83 ± 1.18 | 13.36 | 9.01 | 8.92 ± 1.01 | 11.32 | 10.12 | 81.00 | 80.17 ± 9.98 | 12.45 | −1.02 | 80.27 ± 10.22 | 12.73 | −0.90 | 162.00 | 175.52 ± 20.24 | 11.53 | 8.35 | 176.33 ± 21.61 | 12.26 | 8.85 |
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