Development of a Chemiluminescence Assay for Total N-Terminal Propeptide of Type I Collagen and Its Evaluation in Lung Transplantation

Figure 1

Basic performance evaluation of developed P1NP assay. (a) The calibrator standardization with Roche P1NP assay. The linear correlation of the sample and Roche has a slope of 0.9742. (b) The method comparison of our assay with the Passing–Bablok method between self-developed assay and Roche P1NP assay with slope 0.9803. 94 samples with a range from 15 ng/mL to 1200 ng/mL were included in this study. Dash line means 95% confidence interval. (c) The residual plot analysis of method comparison. The points state the deviation degree of the results obtained from self-developed assay and Roche P1NP assay. The farther the points deviate from zero line means, the larger the deviation exists between the two assays.

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