Research Article

Chemometric Methods for Simultaneous Determination of Candesartan Cilexetil and Hydrochlorothiazide in Binary Combinations

Table 1

Linearity of drugs at all proposed methods.

MethodWavelength (nm)Candesartan cilexetillinearity (µg/mL)Hydrochlorothiazide linearity (µg/mL)

HPSAM2391–461–44
2831–461–44

Q-absorption ratio method2731–461–29
2581–461–44

Correction absorbance method2501–461–44
3401–46