Chemometric Methods for Simultaneous Determination of Candesartan Cilexetil and Hydrochlorothiazide in Binary Combinations

Table 14

Effect of interferences on the Q-absorption ratio method.

λ	Type of interferences	Amount of interferences (µg/mL)	HCT (µg/mL)			CAN (µg/mL)
			Add	Found	%E	Add	Found	%E
273	Polyethylene glycol	100	15	15.36	2.4	15	15.41	2.7
258
273	Sucrose	100	15	14.43	−3.8	15	15.46	3.1
258
273	Lactose	100	15	15.18	1.18	15	15.15	1
258
273	Starch	100	15	14.9	−0.6	15	15.4	2.9
258
273	NaHCO3	100	15	14.97	−0.2	15	15.36	2.8
258
273	All of above	100	15	15.25	1.68	15	14.8	−1.3
258