Chemometric Methods for Simultaneous Determination of Candesartan Cilexetil and Hydrochlorothiazide in Binary Combinations

Table 9

Accuracy of the correction absorbance method in the determination of HCT and CAN.

λ	Hydrochlorothiazide (µg/mL)			Candesartan cilexetil (µg/mL)
	Add	Found	%E	Add	Found	%E
340	15	15.12	0.8	11	11.01	0.1
250
340	15	14.45	−3.66	13	12.7	−2.29
250
340	15	15.31	2.06	15	14.86	−0.95
250
340	17	16.54	−2.73	15	14.6	2.6
250
340	19	19.51	2.67	15	14.87	−0.9
250

¹ calculated using the regression equation of Y = 0.0054x + 0.0067 and the HCT calibration curve at 340 nm. ² calculated using the regression equation of Y = 0.0295x + 0.0648 and the HCT calibration curve at 250 nm.