A LC-MS/MS Method for Quantifying the Schisandrin B and Exploring Its Intracellular Exposure Correlating Antitumor Effect

<table class="table-group" id="tab1"><tr><td><table class="table"><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr class="thead"><td class="align_left">Analytes</td><td class="align_center">MRM transition (<i>m</i>/<i>z</i>) (<i>Q</i>1 ⟶ <i>Q</i>3)</td><td class="align_center">Fragmentor (V)</td><td class="align_center">CE (eV)</td><td class="align_center">Retention time (min)</td></tr><tr><td class="thead-hr" colspan="5"><hr/></td></tr><tr><td class="align_left">Sch.B</td><td class="align_center">401.6 ⟶ 301.3</td><td class="align_center">135</td><td class="align_center">23</td><td class="align_center">2.43</td></tr><tr><td class="align_left">IS</td><td class="align_center">309.1 ⟶ 163</td><td class="align_center">90</td><td class="align_center">12</td><td class="align_center">1.76</td></tr><tr class="table-tr"><td colspan="5"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

<div>Mass spectrometry parameters of analyte and IS.</div>

Journal of Analytical Methods in Chemistry

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Table 1

Table 1: A LC-MS/MS Method for Quantifying the Schisandrin B and Exploring Its Intracellular Exposure Correlating Antitumor Effect 