UVA Exposure Combined with Glycation of the Dermis Are Two Catalysts for Skin Aging and Promotes a Favorable Environment to the Appearance of Elastosis

Figure 5

In vitro and in vivo observations related with possible deleterious effect of glycation combined with the UVA irradiation. Elastin (grey) and pentosidine (pink) immunostainings of different forearm human skin. Note that positive labelling for elastin and pentosidine (as shown by the arrow) increased with age and photoexposure (bar = 100 µm). The main changes observed in human skin in function of age and photoexposure that could partly be explained by transposition with our in vitro results.