Genetic and Epigenetic Tumor Suppressor Gene Silencing Are Distinct Molecular Phenotypes Driven by Growth Promoting Mutations in Nonsmall Cell Lung Cancer
Figure 2
Model of the molecular
phenotypes of NSCLC driven by promoter hypermethylation propensity. The model
depicts the inverse relationship between epigenetic and genetic alterations and its
positive association between epigenetic propensity and growth promoting
oncogene activation.