Genetic and Epigenetic Tumor Suppressor Gene Silencing Are Distinct Molecular Phenotypes Driven by Growth Promoting Mutations in Nonsmall Cell Lung Cancer
Table 1
Demographics of the NSCLC case series.
Characteristic
Age, mean (SD)
66.9(10.6)
Gender, n (prevalence)
Female
80(0.45)
Male
97(0.55)
Histology, n (prevalence)
Adenocarcinoma
95(0.54)
Adeno-squamous
5(0.03)
Bronchoalveolar
2(0.01)
Large cell
14(0.08)
Squamous cell
61(0.34)
Tumor TNM stage, n (prevalence)
Stage 1
99(0.56)
Stage 2
34(0.19)
Stage 3
39(0.22)
Stage 4
5(0.03)
Smoking status, n (prevalence)
Never
13(0.07)
Former
93(0.52)
Current
71(0.40)
KRAS codon 12 mutation, n (prevalence)
No
147(0.83)
Yes
30(0.17)
3p21 LOH fraction allelic loss score, n (prevalence