Research Article

Assessing Candidate Gene nsSNPs for Phenotypic Differences in Double-Strand Break Repair Using Radiation-Induced H2A.X Foci

Figure 1

(a)Representative cell irradiated with 1.5 Gy and incubated for 1 hour following exposure. Left panel: unadjusted, noncompressed image viewed under the DAPI channel; middle panel: unadjusted, noncompressed image viewed under the FITC channel; right panel: adjusted, composite image. The composite image underwent a series of image processing operations including the use of nonlinear algorithms and application of a counterstain mask. (b) Each of the four panels in this image displays a different, representative cell from each time point in sequence from left to right: preexposure, 1 hour, 3 hours, and 24 hours after 1.5 Gy gamma irradiation. All represent adjusted composite images.
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(a)
387423.fig.001b
(b)