Total Cost Coef. 95% CI Lower Upper First-line therapy Chemotherapy alone Rituximab plus chemotherapy $20,971 $9,089 $32,659 Age at diagnosis (years) 66–70 71–75
−
$
2,912
−
$
1
5,466$8,729 76–80 $773
−
$
11,864$13,465 >80
−
$
7,929
−
$
22,218$7,109 Gender Male Female
−
$
3,782
−
$
1
3,154$5,274 Race/ethnicity White Black $8,251
−
$
3
1,012$52,301 Hispanic $21,353
−
$
9,712$55,955 Other
−
$
2
5,380
−
$
4
5,449
−
$
3,296Year of diagnosis 1999–2002 2003–2005
−
$
1,968
−
$
6,478$2,424 Stage at FL diagnosis I & II III & IV $13,947 $3,943 $23,806 Histology (grade) 1 2 $1,440
−
$
1
4,298$18,830 3
−
$
4,210
−
$
1
8,063$10,882 4
−
$
6,924
−
$
2
0,108$6,774 Extranodal involvement No Yes $16,683 $6,307 $27,617 Presence of “B” symptoms No Yes $7,654 −$6,707 $21,571 Anemia No Yes $24,622 −$7,946 $62,434 NCI Comorbidity index 0 1 $7,999 −$3,871 $19,294 2 $7,787 −$8,899 $26,799 ≥3 $60,399 −$13,310 $137,762 Performance status indicators None ≥1 $10,882 −$5,310 $26,939 Percent in census tract with some college <25% ≥25% −$4,875 −$15,504 $5,380 Percent in census tract living in poverty <5% 5–7% $2,021 −$12,003 $17,365 8–12% $5,296 −$7,066 $17,032 >12% $7,107 −$5,484 $18,882 Type of geographic area Large metropolitan Metropolitan −$6,202 −$16,529 $4,807 Urban −$14,949 −$33,514 $3,791 Less urban/rural −$13,777 −$27,682 $49
