Research Article
Impact of Diabetes Status and Medication on Presentation, Treatment, and Outcome of Stage II Colon Cancer Patients
Table 2
Pathologic features of diabetes patients: metformin and insulin treated subsets.
| | Metformin group
| Insulin group
| p
value |
| Median age in years (range) | 73.4 (51.1–93.3) | 71.8 (39.6–85.3) | 0.28 | Sex | | | | Female (%) | 41 (41.4%) | 3 (12.5%) | 0.008 | Male (%) | 58 (58.6%) | 21 (87.5%) | Site | | | | Right colon (%) | 59 (60%) | 14 (58%) | 1.0 | Left colon (%) | 40 (40%) | 10 (42%) | T4 staging (%) | 17 (17.2%) | 4 (16.7%) | 1.0 | <12 lymph node sampling | 28 (28.3%) | 7 (29.2%) | 0.09 | Poor differentiation (%) | 25 (25.2%) | 2 (8.3%) | 0.7 | Lymphovascular invasion | 21 (21.2%) | 4 (16.7%) | 1.0 | MSI status (%) | | | | MSI-stable | 36 (36.4%) | 9 (37.5%) | 1.0 | MSI-high | 18 (18.2%) | 4 (16.7%) | Not done | 43 (43.4%) | 11 (45.8%) | Unknown | 2 (2.0%) | 0 | Emergency presentationa | 11 (11.1%) | 6 (25.0%) | 0.09 |
|
|
aEmergency presentation includes bowel perforation or bowel obstruction.
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