Impact of Diabetes Status and Medication on Presentation, Treatment, and Outcome of Stage II Colon Cancer Patients
Table 4
Univariate and multivariate analyses for recurrence-free survival.
Clinicopathological variablea
Univariate model
Multivariate model
HRb
95% CIc
HRb
95% CIc
Age
60 years
1.00
0.87–2.02
0.184
1.00
0.86–2.14
0.193
60 years
1.33
1.35
Diabetes
No diabetes
1.00
0.74–1.60
0.667
1.00
0.65–1.49
0.93
Diabetes
1.09
0.98
T stage
T3
1.00
1.65–3.41
<0.001
1.00
1.36–2.94
<0.001
T4
2.37
2.00
Lymph node yield
12
1.00
1.01–2.02
0.043
1.00
0.89–1.89
0.169
12
1.43
1.30
Lymphovascular invasion
Absent
1.00
1.57–3.12
<0.001
1.00
1.43–2.89
<0.001
Present
2.21
2.03
Emergency presentation
No
1.00
1.21–2.75
0.004
1.00
1.07–2.49
0.022
Yes
1.82
1.63
aMicrosatellite instability status was not included in the regression models for lack of complete data (complete data in 52% of patients). bHazard ratio. cConfidence interval.