Research Article

Bioactive Volatile Content of the Stem and Root of Centaurea carduiformis DC. subsp. carduiformis var. carduiformis

Table 2

The antiproliferative effect of hexane extract of C. carduiformis in C6, Vero, and HeLa cells*.

C6VeroHeLa
1000 μg/mL500 μg/mL1000 μg/mL500 μg/mL1000 μg/mL500 μg/mL

Control 2 . 0 1 ± 0 . 3 4 a 2 . 1 8 ± 0 . 2 1 a 2 . 0 6 ± 0 . 2 5 a 2 . 2 8 ± 0 . 2 5 a 1 . 5 8 ± 0 . 4 1 a 1 . 5 1 ± 0 . 5 2 a
DMSO 1 . 4 1 ± 0 . 4 9 b 1 . 7 5 ± 0 . 3 5 a 1 . 0 6 ± 0 . 1 6 b 2 . 0 6 ± 0 . 1 3 a 0 . 7 4 ± 0 . 4 7 b 1 . 0 5 ± 0 . 4 3 a
CCS 0 . 1 9 ± 0 . 0 6 c 0 . 5 1 ± 0 . 2 5 b 0 . 2 4 ± 0 . 0 7 c 0 . 3 8 ± 0 . 0 3 b 0 . 2 0 ± 0 . 0 5 b 0 . 2 8 ± 0 . 0 2 b
CCR 0 . 2 1 ± 0 . 0 7 c 0 . 2 1 ± 0 . 0 5 b 0 . 2 2 ± 0 . 0 2 c 0 . 2 1 ± 0 . 0 4 b 0 . 1 7 ± 0 . 0 8 b 0 . 1 7 ± 0 . 0 5 b

*Cells were treated with CCS and CCR (1000–500 μg/mL) in combination with BrdU for 48 hrs, 𝑃 < 0 . 0 5 .