Synthesis and Antimicrobial Activity of Some [1,2,4]-Triazole Derivatives

Table 1

Antibacterial activity of the compounds (8), (9a–c), (10a–e), and (11a–c).

		MIC of the compounds in 𝜇g/mL
Compounds	Gram-positive organisms			Gram-negative organisms
	B. subtilis	S. aureus	S. epidermidis	E. coli	P. aeruginosa
8	18.75	18.75	18.75	18.75	18.75
9a	18.75	18.75	18.75	18.75	9.75
9b	37.5	37.5	37.5	37.5	18.75
9c	37.5	37.5	37.5	37.5	18.75
10a	150	150	75	150	75
10b	150	75	75	150	75
10c	150	75	75	150	75
10d	150	75	150	150	37.5
10e	37.5	37.5	37.5	37.5	18.75
11a	37.5	18.75	18.75	18.75	18.75
11b	18.75	9.75	18.75	9.75	37.5
11c	150	37.5	75	150	37.5
Streptomycin	6.25	1.56	1.562	3.125	3.125
Pencillin	1.526	6.25	3.125	6.25	12.5