Synthesis and Antimicrobial Activity of Some [1,2,4]-Triazole Derivatives

Table 2

Antifungal activity of the compounds (8), (9a–c), (10a–e), and (11a–c).

		MIC of the compounds in 𝜇g/mL
Compound	R. oryzae	A. niger	A. flavus	C. albicans	S. cerevisiae
8	18.75	18.75	150	150	150
9a	37.5	150	75	150	150
9b	150	150	150	37.5	150
9c	18.75	150	150	75	150
10a	150	150	150	150	150
10b	75	75	75	150	150
10c	75	37.5	75	150	150
10d	37.5	37.5	150	150	150
10e	18.75	150	37.5	150	150
11a	37.5	75	75	150	150
11b	75	37.5	75	75	150
11c	37.5	150	150	150	150
Amphotericin-B	1.562	1.56	6.25	6.25	6.25

MIC, 𝜇g/mL: minimum inhibitory concentration.