Microwave-Assisted Synthesis of Isopropyl β-(3,4-Dihydroxyphenyl)-α-hydroxypropanoate

Table 8

Orthogonal experiment on synthesis of isopropyl 𝛽-(3,4-dihydroxyphenyl)-𝛼-hydroxypropanoate.

Trial no.	Factor A; temperature (°C)	Factor B; time (min)	Factor C; MW power (W)	Yield (%)
1	1	1	1	48.5
2	1	2	2	83.2
3	1	3	3	57.4
4	2	1	2	49.5
5	2	2	3	59.1
6	2	3	1	86.1
7	3	1	3	69.3
8	3	2	1	57.7
9	3	3	2	80.2
𝐾1	189.1	167.3	192.3	𝐾=591
𝐾2	194.7	200.0	212.9	𝑃=38809
𝐾3	207.2	223.7	185.8
U	38866.2	39343.7	38942.4
Q	57.2	534.7	133.4