Development and In Vitro Characterization of Hyaluronic Acid-Based Coatings for Implant-Associated Local Drug Delivery Systems

Table 2

Water uptake of EDC/NHS- and GDA-crosslinked HA coatings (𝑛=3) after different swelling times in 1 mL PBS/Tween 20. Data shown in mg water per mg coating as mean ± SD.

Swelling time	EDC/NHS-crosslinked; HA coating	GDA-crosslinked; HA coating
1 min	5.04 ± 0.17	1.90 ± 0.25
2 min	5.27 ± 0.70	2.61 ± 0.15
1 h	6.78 ± 0.39	3.21 ± 0.33