K_𝟕Na_𝟑P_𝟐W_𝟏𝟖Cu_𝟒O_𝟔𝟖: A Mild, Efficient, and Reusable Catalyst for the One-Pot Synthesis of 1,2,4,5-Tetra Substituted Imidazoles

Table 3

Synthesis of 1,2,4,5-tetra substituted imidazoles under different conditions.

Product	Ar	R	Time (h)	Yield (%)	Mp (fou.)	Mp (rep.)
5-a	Ph	CH2Ph	1.5	92	162–164	163–165 [20]
5-b	Ph	Ph	1.5	87	212	216–218 [23]
5-c	3-NO2-C6H4	Ph	2	82	245–247	244–246 [18]
5-d	3-NO2-C6H4	4-CH3-Ph	2	80	148–150	149–151 [19]
5-e	4-NO2-C6H4	Ph	2	80	195–197	192–195 [21]
5-f	4-NO2-C6H4	4-CH3-Ph	2	80	220–222	218–220 [22]
5-g	4-OH-C6H4	Ph	1.5	90	285-286	281–283 [26]
5-h	4-OH-C6H4	CH2Ph	1.5	92	132–134	134-135 [24]
5-i	2-OH-C6H4	CH2Ph	1.5	95	148-149	147-148 [25]
5-j	2-OH-C6H4	4-CH3-Ph	1.5	90	222–224	226–228 [19]
5-k	2-OCH3-C6H4	Ph	1.5	90	149–152	—
5-l	2-OCH3-C6H4	CH2Ph	1.5	92	175–178	—