K_𝟕Na_𝟑P_𝟐W_𝟏𝟖Cu_𝟒O_𝟔𝟖: A Mild, Efficient, and Reusable Catalyst for the One-Pot Synthesis of 1,2,4,5-Tetra Substituted Imidazoles

Table 4

Comparison of different catalysts in the synthesis 1,2,4,5-tetra substituted imidazoles.

No.	Catalyst	Conditions	Time (h)	Yield (%) [Ref.]
1	K5COW12O40,3H2O	140^°C	2–2.5	80–93 [19]
2	Silica gel/NaHSO4	140^°C	2	85–92 [17]
3	High surface SiO2	CH2Cl2/sun light	2–2.5	84–93 [28]
4	InCl3-3H2O	MeOH/R.T	8–9.5	69–82 [29]
5	L-Proline	Reflux in MeOH	8.5–10	78–88 [27]
6	DABCO	t-ButOH/65^°C	12–15	70–82 [30]
7	HPA/silica	140^°C	2	85 [22]
8	MPS	H2O-MeOH/R.T	4–6	84–90 [32]
9	PEG-400	Reflux	1.5–2	89–96 [36]
10	Carbon-based/solid acid	130^°C	2	93 [39]
11	K7Na3P2W18Cu4O68	140^°C	1.5–2	Present work